Cholinergic/Adrenergic drugs — Flashcards

Flashcard 311: What drug is used for chronic pain in tension headaches? _____

Answer: Amitriptyline

Flashcard 312: What effect do alpha-2 agonists have on sympathetic tone?

Answer: Decreased (sympatholytic)

Flashcard 313: What drug class do venlafaxine and desvenlafaxine belong to?_____

Answer: SNRIs

Flashcard 314: _____ are glaucoma drugs that are associated with ocular hyperemia, foreign body sensation, and ocular pruritis

Answer: a2-agonists

Flashcard 315: What is a lethal complication of cholinesterase inhibitor poisoning if untreated?_____

Answer: Respiratory failure

Flashcard 316: Glycopyrrolate is a(n) _____ antagonist

Answer: Muscarinic

Extra: Glycopyrrolate is a **non-selective** muscarinic antagonist. It is a **quaternary ammonium** compound, meaning it does not cross the blood-brain barrier and has minimal CNS side effects (unlike atropine). It is often used to reduce secretions (antisialogogue) and to prevent bradycardia during the reversal of neuromuscular blockade.

Flashcard 317: What drug class does bupropion belong to?_____

Answer: Atypical antidepressants

Flashcard 318: Phenylephrine causes reflex _____ (HR)

Answer: bradycardia

Flashcard 319: Glycopyrrolate can be used to treat _____ disease when taken orally

Answer: peptic ulcer

Flashcard 320: Which neurotransmitter's release is prevented by the Botulinum toxin from Clostridium botulinum?_____

Answer: Acetylcholine