Cholinergic/Adrenergic drugs — Flashcards

Flashcard 461: Are anti-cholinergic effects more common with high or low potency typical antipsychotics? _____

Answer: Low potency

Flashcard 462: Homatropine is _____ antagonist used as a cycloplegic / mydriatic

Answer: muscarinic (general class)

Flashcard 463: Methylphenidate is an amphetamine derivative used to treat _____

Answer: ADHD

Flashcard 464: What drug class does donepezil belong to?_____

Answer: Acetylcholinesterase inhibitor

Flashcard 465: What G-protein is the M3 muscarinic receptor coupled to? _____

Answer: Gq

Flashcard 466: Activation of the alpha-1 (α1) adrenergic receptor may cause urinary _____

Answer: retention

Flashcard 467: Rank the following receptors for affinity to **norepinephrine**, from highest to lowest: α1, β1, β2

Answer: α1 > β1 > β2

Extra: Norepinephrine is a potent agonist at α1, α2, and β1 receptors, but has negligible activity at β2 receptors. Contrast this with Epinephrine, which has significant activity at all four receptors (α1, α2, β1, β2).

Flashcard 468: Isoproterenol causes _____ mean arterial pressure

Answer: decreased