Cholinergic/Adrenergic drugs — Flashcards

Flashcard 461: Homatropine is _____ antagonist used as a cycloplegic / mydriatic

Answer: muscarinic (general class)

Flashcard 462: Methylphenidate is an amphetamine derivative used to treat _____

Answer: ADHD

Flashcard 463: Are anti-cholinergic effects more common with high or low potency typical antipsychotics? _____

Answer: Low potency

Flashcard 464: What G-protein is the M3 muscarinic receptor coupled to? _____

Answer: Gq

Flashcard 465: Activation of the alpha-1 (α1) adrenergic receptor may cause urinary _____

Answer: retention

Flashcard 466: Rank the following receptors for affinity to **norepinephrine**, from highest to lowest: α1, β1, β2

Answer: α1 > β1 > β2

Extra: Norepinephrine is a potent agonist at α1, α2, and β1 receptors, but has negligible activity at β2 receptors. Contrast this with Epinephrine, which has significant activity at all four receptors (α1, α2, β1, β2).

Flashcard 467: Pilocarpine is a potent _____ of tears, sweat, and salivary secretion

Answer: stimulator

Flashcard 468: What drug class does donepezil belong to?_____

Answer: Acetylcholinesterase inhibitor