Cholinergic/Adrenergic drugs — Flashcards

Flashcard 451: Is phentolamine (alpha-blocker) selective or non-selective?

Answer: Non-selective

Flashcard 452: Which type of acetylcholine receptors (muscarinic or nicotinic) are found in effector tissues (e.g., heart, smooth muscle, brain, and glands)?

Answer: Muscarinic

Flashcard 453: Typical antipsychotics exert their effects by blocking the _____ receptor

Answer: D2 dopamine

Flashcard 454: Rank the following receptors based on their affinity for dobutamine (from highest to lowest): β1, β2, α1

Answer: β1 > β2 > α1

Extra: Dobutamine is a synthetic sympathomimetic that is relatively selective for β1 receptors. Its potency at β1 is significantly greater than at β2 or α1 receptors. At clinical doses, dobutamine primarily increases cardiac contractility (inotropy) with a lesser effect on heart rate (chronotropy).

Flashcard 455: Oxybutynin and tolterodine are primarily used to treat _____

Answer: urgency incontinence (overactive bladder)

Flashcard 456: Is carbachol a muscarinic or nicotinic Ach agonist? _____

Answer: Both

Flashcard 457: Levodopa and other Parkinson therapies are contraindicated in _____ patients

Answer: psychotic

Flashcard 458: Carbidopa _____ the neuropsychiatric side effects of levodopa

Answer: exacerbates

Flashcard 459: Methylphenidate is an amphetamine derivative used to treat _____

Answer: ADHD

Flashcard 460: Homatropine is _____ antagonist used as a cycloplegic / mydriatic

Answer: muscarinic (general class)