Cholinergic/Adrenergic drugs — Flashcards

Flashcard 441: One adverse effect of anti-muscarinics is _____, especially in men with prostatic hyperplasia

Answer: urinary retention

Flashcard 442: Which cholinesterase inhibitor poisoning antidote reverses the central muscarinic effects?_____

Answer: Atropine

Flashcard 443: What effect does atropine have on the stomach acid secretion?_____

Answer: Decreased acid secretion

Flashcard 444: What effect do anti-muscarinics have on accommodation? _____

Answer: Inhibition (cycloplegia)

Flashcard 445: Treatment of cystic fibrosis includes _____, a beta-2 agonist

Answer: albuterol

Flashcard 446: Anti-cholinergic medication effects (e.g., TCAs) result in _____ compound muscle action potential following motor nerve stimulation

Answer: no change in

Flashcard 447: What type of adrenergic receptor is found on the renal afferent and efferent arterioles? _____

Answer: Alpha-1 adrenergic receptors

Flashcard 448: Typical antipsychotics are associated with _____, such as acute dystonia, akithisia, and Parkinsonism

Answer: extrapyramidal symptoms

Flashcard 449: Oxybutynin and tolterodine are primarily used to treat _____

Answer: urgency incontinence (overactive bladder)

Flashcard 450: Rank the following receptors based on their affinity for dobutamine (from highest to lowest): β1, β2, α1

Answer: β1 > β2 > α1

Extra: Dobutamine is a synthetic sympathomimetic that is relatively selective for β1 receptors. Its potency at β1 is significantly greater than at β2 or α1 receptors. At clinical doses, dobutamine primarily increases cardiac contractility (inotropy) with a lesser effect on heart rate (chronotropy).