Cholinergic/Adrenergic drugs — Flashcards

Flashcard 291: Adverse effects of paroxetine include anti-_____ effects, sleep disturbances (abnormal dreams), and sexual dysfunction

Answer: cholinergic

Extra: Paroxetine is unique among SSRIs for having significant anticholinergic activity. While most SSRIs primarily cause GI upset (nausea), sexual dysfunction, and sleep disturbances, paroxetine's side effect profile also includes dry mouth and constipation due to its muscarinic antagonism. Note: Vortioxetine (the drug previously listed on this card) is an atypical antidepressant that lacks significant anticholinergic effects and is most commonly associated with nausea.

Flashcard 292: Phenylephrine causes _____ systolic pressure

Answer: increased

Flashcard 293: Guanfacine differs from Clonidine in that is it _____ by cytochrome p450

Answer: metabolized (metabolized or not metabolized?)

Flashcard 294: What demographic is associated with organophosphate poisoning? _____

Answer: Farmers

Flashcard 295: Acetylcholinesterase inhibitors may be used to treat urinary _____

Answer: retention

Flashcard 296: Phenylephrine may be used as a _____ for ocular procedures

Answer: mydriatic

Flashcard 297: Is bupropion use associated with sexual dysfunction? _____

Answer: No

Flashcard 298: The _____ muscarinic receptor is found in glands, the bladder, and smooth muscle

Answer: M3

Flashcard 299: Glycopyrrolate is an _____ receptor antagonist that is used to reduce activity of glands

Answer: M3 (specific receptor)

Flashcard 300: Cholinomimetic drugs mimic the neurotransmitter _____

Answer: acetylcholine