Central Nervous System Pharmacology — Flashcards

As a result of inhibition of VDCCs (N-type Ca2+ channels) located on the _____ membrane of neurons, pregabalin results in decreased neurotransmission

The inverse agonist of the _____ receptor is beta-carboline

Anticonvulsants _____ and brivaracetam act on SV2A proteins and modulates GABA and glutamate release

Vilazodone is a _____ receptor partial agonist

_____ is an exotoxin from Clostridium tetani that cleaves SNARE proteins required for neurotransmitter release.

Neuro/Psych _____ is an anti-epileptic associated with hirsutism in women

Calcium Channel Blockers (CCBs) _____ is a Ca2+ channel blocker that is used to prevent cerebral vasospasm following a subarachnoid hemorrhage

Neuro/Psych_____, barbiturates, and alcohol all bind different allosteric sites of the GABAA receptor

Neuro/Psych _____ and trihexyphenidyl are antimuscarinic agents used to treat Parkinsonism

1st generation H1 receptor antagonists, especially _____, may be used as a sleep aid