Central Nervous System Pharmacology — Flashcards

Neuro/Psych_____ is a competitive antagonist at the benzodiazepine site of the GABA-A receptor, which is used to treat overdose or reverse sedative effects of benzodiazepines AND nonbenzodiazepine hypnotics

The symptoms of _____ syndrome can be remembered with the "3 A's": 1. neuromuscular hyperActivity (clonus, hyperreflexia, hypertonia, tremor, seizure) 2. Autonomic stimulation (hyperthermia, diaphoresis, diarrhea)3. Agitation

_____ is a 5-HT1A partial agonist while vortioxetine is a 5-HT1A agonist/5-HT3 antagonist.

The exotoxin _____ inhibits inhibitory neurons, resulting in lack of GABA and Glycine release

_____ is an anti-epileptic drug that can cause hemophagocytic lymphohistiocytosis (HLH), a serious immune system reaction.

Antihistamines: _____ generation H1 receptor antagonists may stimulate appetite and cause weight gain due to anti-serotonergic effects.

First Aid Pharmacology: Neuro/Psych _____ and topiramate are anti-epileptics that are useful for migraine prophylaxis

Pharmacologic treatment of Idiopathic intracranial hypertension often involves _____ or topiramate

_____ generation cephalosporins are able to penetrate the CNS

Ramelteon binds the _____ and MT2 receptors in the suprachiasmatic nucleus of the hypothalamus