General Anesthetics — Flashcards

Flashcard 1: _____ subunit of the GABAA receptors mediate anxiolysis and muscle relaxation

Answer: 2

Flashcard 2: All local anesthetics are vasodialators except _____

Answer: cocaine

Flashcard 3: Lidocaine, Mepivacaine and Prilocaine are _____ acting local anesthetics

Answer: intermediate

Flashcard 4: _____ is the most potent, most toxic and longest acting local anaesthetic agent

Answer: Dibucaine

Flashcard 5: Acting via GABA-_____ receptors, GABA increases Cl conductance.

Answer: A

Flashcard 6: First Aid Pharmacology: Neuro/Psych Complications of succinylcholine include _____-calcemia, hyper-kalemia, and malignant hyperthermia

Answer: hyper

Flashcard 7: _____ amphetamine use will decrease the minimum alveolar concentration for an anaesthetic agent

Answer: Chronic (Acute/Chronic)

Flashcard 8: Drug of choice for malignant neuroleptic syndrome:

Answer: Dantrolene

Flashcard 9: Sodium valproate mechanism of action: 1. Blocks voltage-gated _____ channels. 2. Increases the concentration of GABA in the brain. 3. Inhibits T-type calcium (Ca2+) channels.

Answer: sodium (Na+)

Extra: Sodium valproate is a broad-spectrum anticonvulsant used for generalized (including absence) and focal seizures. It increases GABA levels by inhibiting GABA transaminase and stimulating glutamic acid decarboxylase. It also inhibits T-type Ca2+ channels in the thalamus, which explains its efficacy in absence seizures.

Flashcard 10: The given plant is? _____

Answer: Erythroxylum coca