Psychostimulants — Flashcards

Flashcard 1: Less common but more serious side effects such as mood and behavioural changes are associated with _____

Answer: Levetiracetam (Anti-epileptic)

Flashcard 2: Neuro/Psych_____ increase Cl- conductance by increasing the duration of channel opening (frequency or duration)

Answer: Barbiturates

Flashcard 3: The symptoms of _____ syndrome can be remembered with the "3 A's": 1. neuromuscular hyperActivity (clonus, hyperreflexia, hypertonia, tremor, seizure) 2. Autonomic stimulation (hyperthermia, diaphoresis, diarrhea)3. Agitation

Answer: serotonin

Flashcard 4: Cocaine exerts its effects via inhibition of the _____ and DAT transporters (reuptake inhibitor)

Answer: NET

Flashcard 5: _____ is used in insomnia in blind people, and chronic sleep disorders like non 24-hour sleep wake disorder

Answer: Tasimelteon

Flashcard 6: Theophylline may have CNS side effects including _____ and tremor

Answer: nervousness

Flashcard 7: Cocaine inhibits the reuptake of which neurotransmitters?_____

Answer: Dopamine, Norepinephrine and Serotonin

Flashcard 8: Sodium valproate mechanism of action: 1. Blocks voltage-gated _____ channels. 2. Increases the concentration of GABA in the brain. 3. Inhibits T-type calcium (Ca2+) channels.

Answer: sodium (Na+)

Extra: Sodium valproate is a broad-spectrum anticonvulsant used for generalized (including absence) and focal seizures. It increases GABA levels by inhibiting GABA transaminase and stimulating glutamic acid decarboxylase. It also inhibits T-type Ca2+ channels in the thalamus, which explains its efficacy in absence seizures.

Flashcard 9: The given plant is? _____

Answer: Erythroxylum coca

Flashcard 10: tetanospasmin blocks _____

Answer: presynaptic inhibitory neurotransmitter release

Extra: