Cholinergic/Adrenergic drugs — Flashcards

Flashcard 281: To gauge the degree of _____ induced by neuromuscular junction blocking agents, train of four stimulation can be used during anesthesia

Answer: paralysis

Flashcard 282: What drug class do neostigmine, physostigmine, and pyridostigmine belong to?_____

Answer: Acetylcholinesterase inhibitors

Flashcard 283: Phenylephrine causes _____ systolic pressure

Answer: increased

Flashcard 284: Tolcapone can cause _____ failure as an adverse effect

Answer: hepatic

Flashcard 285: What drug class does edrophonium belong to?_____

Answer: Acetylcholinesterase inhibitor

Flashcard 286: Compared to other antidepressants, bupropion is _____ likely to cause weight gain

Answer: less

Flashcard 287: The detrusor muscle predominantly expresses _____ receptors.

Answer: M3 and B3

Flashcard 288: Muscarinic antagonists cause broncho-_____

Answer: dilation

Flashcard 289: Adverse effects of paroxetine include anti-_____ effects, sleep disturbances (abnormal dreams), and sexual dysfunction

Answer: cholinergic

Extra: Paroxetine is unique among SSRIs for having significant anticholinergic activity. While most SSRIs primarily cause GI upset (nausea), sexual dysfunction, and sleep disturbances, paroxetine's side effect profile also includes dry mouth and constipation due to its muscarinic antagonism. Note: Vortioxetine (the drug previously listed on this card) is an atypical antidepressant that lacks significant anticholinergic effects and is most commonly associated with nausea.

Flashcard 290: Mirabegron is indicated for _____

Answer: urinary urge incontinence