Autonomic/CV Drugs — Flashcards

Flashcard 811: Vigabatrin is an anti-epileptic that exerts its effects via inhibition of the enzyme _____

Answer: GABA transaminase

Extra: Sketchy Pharmacology: Neuro/Psych

Flashcard 812: _____-dose Aspirin and Diuretics decrease uric acid secretion

Answer: Low

Flashcard 813: In addition to ethosuximide, absence seizures may also be treated with _____ and lamotrigine

Answer: valproic acid

Extra: Sketchy Pharmacology: Neuro/Psych

Flashcard 814: What effect do cardiac glycosides have on intracellular Na+ concentration? _____

Answer: Increased

Flashcard 815: Milrinone and inamrinone are _____ inhibitors used in the treatment of acute heart failure

Answer: PDE-3

Extra: Milrinone and inamrinone are PDE-3 inhibitors. Mechanism: - Cardiac: ↑ cAMP → ↑ inotropy and lusitropy. - Vascular: ↑ cAMP → vasodilation (decreased preload and afterload). - Often referred to as "inodilators." Clinical Use: Acute heart failure support.

Flashcard 816: Which direct thrombin inhibitor is administered orally? _____

Answer: Dabigatran

Flashcard 817: The most common complication of insulin therapy is _____; may also experience lipodystrophy and hypersensitivity reaction (rare)

Answer: hypoglycemia

Extra: Sketchy Pharmacology: Endocrine (diabetes)

Flashcard 818: Class III antiarrhythmics (K+ channel blockers) exert their effects by prolonging phase _____ and _____ of the myocardial action potential

Answer: 2

Extra: Sketchy Pharmacology: Cardiovascular (Antiarrhythmics)

Flashcard 819: Steroid diabetes may be seen in patients on _____ therapy

Answer: glucocorticoid

Flashcard 820: The effect of intermediate dose aspirin _____ mg/day is antipyretic and analgesic

Answer: 300-2400