Positive inotropic agents — Flashcards

10 flashcards

Cardiac glycosides (e.g. digoxin) exert their effects via inhibition of the _____ pump

Cardiac glycosides (e.g. digoxin) cause _____ cardiac contractility due to increased sarcoplasmic Ca2+ stores

Unlike phenylephrine, norepinephrine causes increased _____ due to beta-1 activation which results in increased pulse pressure

ACE inhibitors, Beta-blockers (compensated HF), and Aldosterone Antagonists are beneficial in Heart Failure because they help prevent:

What sympathomimetic is used to treat cardiogenic shock? _____

What effect does milrinone have on cardiac contractility? _____

Dopamine may be used for the treatment of _____ failure and unstable bradycardia

vardenafil

sildenafil

#10

What is the effect of high-dose Aspirin (salicylates) on oxidative phosphorylation?

Positive inotropic agents US Medical PG Flashcards - Medical Study Cards

Master Positive inotropic agents with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.

Positive inotropic agents Flashcard Deck - 10 Cards

Flashcard 1: Cardiac glycosides (e.g. digoxin) exert their effects via inhibition of the _____ pump

Answer: Na+-K+ ATPase

Flashcard 2: Cardiac glycosides (e.g. digoxin) cause _____ cardiac contractility due to increased sarcoplasmic Ca2+ stores

Answer: increased

Flashcard 3: Unlike phenylephrine, norepinephrine causes increased _____ due to beta-1 activation which results in increased pulse pressure

Answer: cardiac contractility

Flashcard 4: ACE inhibitors, Beta-blockers (compensated HF), and Aldosterone Antagonists are beneficial in Heart Failure because they help prevent:

Answer: Cardiac remodeling

Extra: These drug classes (ACE inhibitors, Beta-blockers, and Aldosterone Antagonists) have been shown to reduce mortality in patients with heart failure by preventing or reversing maladaptive cardiac remodeling.

Flashcard 5: What sympathomimetic is used to treat cardiogenic shock? _____

Answer: Dobutamine

Flashcard 6: What effect does milrinone have on cardiac contractility? _____

Answer: Increased contractility

Flashcard 7: Dopamine may be used for the treatment of _____ failure and unstable bradycardia

Answer: heart

Flashcard 8: vardenafil

Answer: PDE5 inhibitor

Extra: erectile dysfunctionpatients taking nitrates (lethal hypotension)inhbit phosphodiesterase 5, resulting in increased cGMP and smooth muscle relaxation in corpus cavernosumheadache, flushing, impaired blue-green color vision, hypotension, dyspepsia

Flashcard 9: sildenafil

Answer: PDE5 inhibitor

Flashcard 10: What is the effect of high-dose Aspirin (salicylates) on oxidative phosphorylation?

Answer: Uncouples oxidative phosphorylation (increases permeability of the inner mitochondrial membrane)

Extra: Aspirin (salicylates) in high doses uncouples oxidative phosphorylation, leading to a decreased ATP production and increased heat production (fever). It also contributes to the metabolic acidosis seen in salicylate toxicity.

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Positive inotropic agents Flashcards for USMLE

Study 10 flashcards on Positive inotropic agents for USMLE Pharmacology. These active recall cards cover the key concepts, clinical associations, and high-yield facts from this chapter of Autonomic/CV Drugs. Each card is designed to test your understanding rather than just recognition, building stronger and more durable memories for exam day.

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There are 10 flashcards for Positive inotropic agents, covering the key concepts, clinical correlations, and high-yield facts from this chapter of Autonomic/CV Drugs.

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