Autonomic/CV Drugs — Flashcards

Flashcard 761: _____ patients are more sensitive to the side effects of benzodiazepines (e.g. somnolence, confusion, disorientation)

Answer: Elderly

Extra: Sketchy Pharmacology: Neuro/Psych

Flashcard 762: What change in bowel movement is associated with activation of μ-opioid receptors? _____

Answer: Constipation

Extra: Sketchy Pharmacology: Neuro/Psych

Flashcard 763: The E-series prostaglandins are vaso-_____

Answer: dilators

Flashcard 764: Dexamethasone, hydrocortisone, and prednisone are all examples of _____

Answer: glucocorticoids

Extra: Sketchy Pharmacology: Thyroid, Pituitary, & Adrenal

Flashcard 765: What type of local anesthetic are lidocaine, mepivacaine, and bupivacaine? _____

Answer: Amides

Extra: First Aid Pharmacology: Neuro/Psych

Flashcard 766: 1st generation H1 receptor antagonists may stimulate appetite and cause weight gain due to anti-_____ effects

Answer: serotonergic

Extra: Sketchy Pharmacology: Respiratory (Antihistamines)

Flashcard 767: Nonbenzodiazepine hypnotics work by decreasing _____

Answer: sleep latency

Flashcard 768: Sevelamer is a compound that binds free _____ in the gastrointestinal tract

Answer: phosphate

Flashcard 769: Which diuretics cause an increase in urine NaCl? _____

Answer: All diuretics :)

Extra: First Aid Pharmacology: Renal (Diuretics)

Flashcard 770: What is the formula for calculating **loading dose**?

Answer: Loading dose = (Cp × Vd) / F Cp = target plasma concentration Vd = volume of distribution F = bioavailability

Extra: Loading dose is primarily dependent on the **volume of distribution** (Vd). For a drug given IV, F = 1. In contrast, maintenance dose is primarily dependent on **clearance** (CL).