Autonomic/CV Drugs — Flashcards

Flashcard 751: Compared to other hypnotics, ramelteon has relatively _____ side effects and is _____ to use in geriatric patients

Answer: few

Extra: Sketchy Pharmacology: Neuro/Psych

Flashcard 752: Because Pembrolizumab targets a peripheral tolerance mechanism, patients taking this drug can develop autoimmune disorders of _____ organs

Answer: endocrine

Extra: Pembrolizumab is a PD-1 inhibitor (checkpoint inhibitor). By blocking the PD-1 receptor on T cells, it prevents the tumor from suppressing the immune response, but it can also lead to immune-related adverse events (irAEs) due to the loss of peripheral tolerance.

Flashcard 753: Isoproterenol causes _____ mean arterial pressure

Answer: decreased

Extra: Sketchy Pharmacology: Autonomics (Sympathomimetics)

Flashcard 754: What type of β-blocker is esmolol? _____

Answer: Selective β1 antagonist (cardioselective)

Extra: Sketchy Pharmacology: Autonomics (β-blockers)

Flashcard 755: What effect may acetazolamide have on serum K+ levels? _____

Answer: Decreased (hypokalemia)

Extra: Sketchy Pharmacology: Renal (Diuretics)

Flashcard 756: One possible adverse effect of class IV antiarrhythmics is AV _____ due to decreased conduction through the AV node

Answer: block

Extra: Sketchy Pharmacology: Cardiovascular (Antiarrhythmics)

Flashcard 757: What is the first-line pharmacologic treatment for depression? _____

Answer: SSRIs

Extra: Sketchy Pharmacology: Neuro/Psych

Flashcard 758: Adverse effects of chronic aspirin use include: - _____ injury - acute interstitial nephritis - GI bleeding

Answer: acute renal

Flashcard 759: Monoamine oxidase inhibitors can prevent the metabolism of tyramine (e.g. from wine or cheese ingestion), causing a(n) _____ crisis

Answer: hypertensive

Extra: Sketchy Pharmacology: Autonomics (α drugs)

Flashcard 760: What drug class does isocarboxazid belong to? _____

Answer: Monoamine oxidase inhibitors (MAOIs)

Extra: Sketchy Pharmacology: Neuro/Psych