Autonomic/CV Drugs — Flashcards

Flashcard 2661: Uricosurics (ie: probenecid) treat chronic gout due to _____

Answer: underexcretion

Flashcard 2662: Digoxin is useful in the treatment of _____ fibrillation (and flutter)

Answer: atrial

Flashcard 2663: What is first-line treatment for essential tremor?

Answer: Non-selective beta-blockers (e.g., propranolol)

Flashcard 2664: What drug class do eptifibatide and tirofiban belong to?_____

Answer: GPIIb/IIIa inhibitors

Flashcard 2665: Sildenafil causes cyanopia via inhibition of _____ in the retina.

Answer: PDE-6

Flashcard 2666: Benzodiazepines _____ the action of GABAA (enhance or inhibit)

Answer: enhance

Flashcard 2667: Benzodiazepines can cause central _____, leading to increased risk of falls in the elderly

Answer: ataxia

Flashcard 2668: One adverse effect associated with digoxin is _____ (HR)

Answer: bradycardia

Flashcard 2669: What drug class does lidocaine belong to? _____

Answer: Class IB antiarrhythmics

Flashcard 2670: VEGF RTK inhibitors can cause hyper_____

Answer: tension

Extra: VEGF RTK inhibitors (e.g., sunitinib, sorafenib) and VEGF antibodies (e.g., bevacizumab) commonly cause **hypertension** by decreasing nitric oxide production in the vascular endothelium. Note: While RTK inhibitors specifically can also cause a **hand-foot skin reaction** (characterized by hyperkeratosis), hypertension is the hallmark cardiovascular side effect and aligns with the topic categorization.