Autonomic/CV Drugs — Flashcards

Flashcard 2661: Triptans _____ release of vasoactive peptides

Answer: prevent

Flashcard 2662: Glucocorticoids are useful for _____ therapy (e.g. transplant rejection prevention, treatment of autoimmune disorders)

Answer: immunosuppressive

Flashcard 2663: Typical antipsychotics may cause symptoms of _____ excess (e.g. galactorrhea, amenorrhea, gynecomastia)

Answer: prolactin

Flashcard 2664: Erlotinib is an _____ inhibitor is used to treat NSCLC and Pancreatic cancer

Answer: EGF-R

Flashcard 2665: Which calcineurin inhibitor is associated with an even greater risk for diabetes vs the other calcineurin inhibitors?_____

Answer: Tacrolimus

Flashcard 2666: What drug class does celecoxib belong to?_____

Answer: Selective COX-2 inhibitor

Flashcard 2667: Which chemotherapeutic drug is widely used for the prophylaxis of organ/graft rejection?

Answer: Azathioprine (6-MP)

Flashcard 2668: Do nonbenzodiazepine hypnotics cause significant day-after psychomotor depression and/or amnesia? _____

Answer: No

Flashcard 2669: VEGF RTK inhibitors can cause hyper_____

Answer: tension

Extra: VEGF RTK inhibitors (e.g., sunitinib, sorafenib) and VEGF antibodies (e.g., bevacizumab) commonly cause **hypertension** by decreasing nitric oxide production in the vascular endothelium. Note: While RTK inhibitors specifically can also cause a **hand-foot skin reaction** (characterized by hyperkeratosis), hypertension is the hallmark cardiovascular side effect and aligns with the topic categorization.

Flashcard 2670: What drug class does lidocaine belong to? _____

Answer: Class IB antiarrhythmics