Autonomic/CV Drugs — Flashcards

Flashcard 2631: Which anticoagulant has the greatest efficacy on factor IIa (thrombin)? _____

Answer: Heparin

Flashcard 2632: How can prolactin excess be treated? _____

Answer: dopamine agonists (e.g. bromocriptine)

Flashcard 2633: First Aid Pharmacology: Endocrine_____ is a possible teratogenic complication of methimazole if given in the first trimester

Answer: Aplasia cutis

Flashcard 2634: One adverse effect associated with digoxin is _____ due to parasympathetic activity at AV node

Answer: heart block

Flashcard 2635: Evolocumab binds PCSK9 and _____ degradation of hepatic LDL receptors

Answer: prevents

Flashcard 2636: What type of drug are class III antiarrhythmics? _____

Answer: K+ channel blockers

Flashcard 2637: What opioid analgesic causes mydriasis? _____

Answer: Meperidine

Flashcard 2638: What formula is used to calculate loading dose? _____

Answer: (Cp × Vd) / F

Extra: Cp = Target plasma concentration Vd = Volume of distribution F = Bioavailability Note: Loading dose depends on the **volume of distribution** (Vd). In contrast, maintenance dose depends on **clearance** (CL).

Flashcard 2639: What type of renal tubular acidosis may be caused by K+ sparing diuretics? _____

Answer: Type 4 RTA

Flashcard 2640: What drug class does streptokinase belong to?_____

Answer: Thrombolytics