Autonomic/CV Drugs — Flashcards

Flashcard 2641: How can prolactin excess be treated? _____

Answer: dopamine agonists (e.g. bromocriptine)

Flashcard 2642: Danazol is used to treat _____ and hereditary angioedema

Answer: endometriosis

Flashcard 2643: Which anticoagulant has the greatest efficacy on factor IIa (thrombin)? _____

Answer: Heparin

Flashcard 2644: Typical antipsychotics may cause symptoms of _____ excess (e.g. galactorrhea, amenorrhea, gynecomastia)

Answer: prolactin

Flashcard 2645: What high-yield sexual side effect is associated with **trazodone**?

Answer: Priapism

Extra: Trazodone is a SARI (Serotonin Antagonist and Reuptake Inhibitor) often used for insomnia. It is famously associated with priapism ('Trazo-bone') due to its α1-blocking effects. Notably, it lacks the standard sexual side effects (e.g., decreased libido, anorgasmia) associated with SSRIs.

Flashcard 2646: _____ is an antagonist at breast and uterus and an agonist at bone

Answer: Raloxifene

Flashcard 2647: What drug is given for overdose of dextromethorphan? _____

Answer: Naloxone

Flashcard 2648: What drug class does lidocaine belong to? _____

Answer: Class IB antiarrhythmics

Flashcard 2649: VEGF RTK inhibitors can cause hyper_____

Answer: tension

Extra: VEGF RTK inhibitors (e.g., sunitinib, sorafenib) and VEGF antibodies (e.g., bevacizumab) commonly cause **hypertension** by decreasing nitric oxide production in the vascular endothelium. Note: While RTK inhibitors specifically can also cause a **hand-foot skin reaction** (characterized by hyperkeratosis), hypertension is the hallmark cardiovascular side effect and aligns with the topic categorization.

Flashcard 2650: Do nonbenzodiazepine hypnotics cause significant day-after psychomotor depression and/or amnesia? _____

Answer: No