Autonomic/CV Drugs — Flashcards

Flashcard 241: Prostacyclin analogs (epoprostenol/iloprost) can cause decreased platelet aggregation and are potent _____

Answer: vasodilators

Extra: Prostacyclin (PGI2) inhibits platelet aggregation and promotes vasodilation, opposing the actions of Thromboxane A2 (TXA2).

Flashcard 242: Glucocorticoids may cause _____ due to inhibition of osteoblast activity *bonus: what supplements should be taken to prevent this?

Answer: osteoporosis

Extra: Sketchy Pharmacology: Thyroid, Pituitary, & Adrenal

Flashcard 243: Alpha-glucosidase inhibitors (e.g. acarbose, miglitol) are used to control the _____ glucose spike

Answer: postprandial

Extra: Alpha-glucosidase inhibitors (e.g., acarbose, miglitol) inhibit the brush-border enzyme alpha-glucosidase, delaying carbohydrate hydrolysis and glucose absorption. This primarily reduces postprandial glucose levels. Side effects: GI upset (flatulence, diarrhea) due to fermentation of undigested carbohydrates by colonic flora.

Flashcard 244: Trastuzumab is an IgG monoclonal antibody against the _____ receptor

Answer: Her2/Neu

Flashcard 245: Etanercept is used primarily for the treatment of _____ Arthritis

Answer: Rheumatoid

Flashcard 246: What effect does dobutamine have on HR and contractility? _____

Answer: Increased HR/contractility (β1 agonist)

Extra: Sketchy Pharmacology: Autonomics (Sympathomimetics)

Flashcard 247: _____ and nalbuphine are κ-opioid receptor agonists and μ-opioid receptor antagonists

Answer: Pentazocine

Extra: First Aid Pharmacology: Neuro/Psych

Flashcard 248: Regular insulin is characterized by _____ action and duration

Answer: short

Extra: Sketchy Pharmacology: Endocrine (diabetes)

Flashcard 249: Compared to typical antipsychotics, atypical antipsychotics cause _____ anti-α1 side effects

Answer: less

Extra: Sketchy Pharmacology: Neuro/Psych

Flashcard 250: Deferoxamine, deferasirox, and deferiprone are iron _____

Answer: chelators