Autonomic/CV Drugs — Flashcards

Flashcard 231: Acetazolamide is a diuretic that inhibits the enzyme _____

Answer: carbonic anhydrase

Extra: Sketchy Pharmacology: Renal (Diuretics)

Flashcard 232: What is a **characteristic, dose-dependent** side effect of SNRIs (especially venlafaxine)? _____

Answer: Hypertension

Extra: Sketchy Pharmacology: Neuro/Psych

Flashcard 233: Most opioid analgesics cause _____

Answer: miosis

Extra: Sketchy Pharmacology: Neuro/Psych

Flashcard 234: Prostacyclin analogs (epoprostenol/iloprost) can cause decreased platelet aggregation and are potent _____

Answer: vasodilators

Extra: Prostacyclin (PGI2) inhibits platelet aggregation and promotes vasodilation, opposing the actions of Thromboxane A2 (TXA2).

Flashcard 235: Propranolol is a β-blocker that is useful for the treatment of _____ storm

Answer: thyroid

Extra: Sketchy Pharmacology: Autonomics (β-blockers)

Flashcard 236: Regular insulin is characterized by _____ action and duration

Answer: short

Extra: Sketchy Pharmacology: Endocrine (diabetes)

Flashcard 237: Cyclophosphamide must be bioactivated by the _____ in order to function

Answer: liver

Flashcard 238: _____ and nalbuphine are κ-opioid receptor agonists and μ-opioid receptor antagonists

Answer: Pentazocine

Extra: First Aid Pharmacology: Neuro/Psych

Flashcard 239: Alpha-glucosidase inhibitors (e.g. acarbose, miglitol) are used to control the _____ glucose spike

Answer: postprandial

Extra: Alpha-glucosidase inhibitors (e.g., acarbose, miglitol) inhibit the brush-border enzyme alpha-glucosidase, delaying carbohydrate hydrolysis and glucose absorption. This primarily reduces postprandial glucose levels. Side effects: GI upset (flatulence, diarrhea) due to fermentation of undigested carbohydrates by colonic flora.

Flashcard 240: What is the first-line pharmacologic treatment for obsessive-compulsive disorder (OCD)? _____

Answer: SSRIs

Extra: Sketchy Pharmacology: Neuro/Psych