Autonomic/CV Drugs — Flashcards

Flashcard 2341: Cardiovascular (Antiarrhythmics) _____ is a cardiac glycoside that has antiarrhythmic properties

Answer: Digoxin

Flashcard 2342: Dobutamine causes _____ diastolic pressure

Answer: decreased

Flashcard 2343: First Aid Pharmacology: Neuro/Psych MAO inhibitors may cause CNS _____ (stimulation or depression)

Answer: stimulation

Flashcard 2344: Suvorexant is contraindicated in patients with _____

Answer: Narcolepsy

Flashcard 2345: Motilin receptor agonists, such as _____, are used to stimulate intestinal peristalsis

Answer: erythromycin

Flashcard 2346: What drug class do diphenhydramine and dimenhydrinate belong to?_____

Answer: 1st generation H1 receptor antagonists

Flashcard 2347: Which anti-emetic(s) should be used to treat a patient with nausea/vomiting due to emetogenic substances in the blood/CNS?_____

Answer: 1. D2 receptor blockers, such as metoclopramide 2. NK1 receptor blockers, such as aprepitant

Flashcard 2348: What drug may be used to relieve symptoms due to unstable angina?_____

Answer: Nitroglycerin

Flashcard 2349: Benzodiazepines may have additive CNS depression effects with _____, barbiturates, 1st generation antihistamines, and neuroleptics

Answer: alcohol

Flashcard 2350: NSAIDs increase the risk of GI bleeding primarily through the inhibition of which enzyme?

Answer: COX-1

Extra: Inhibition of **COX-1** leads to: 1. Decreased **PGE2 and PGI2**: Reduces gastric mucosal protection (decreases mucus and bicarbonate secretion, decreases blood flow). 2. Decreased **TXA2**: Inhibits platelet aggregation, which increases the tendency to bleed from any mucosal damage.