Autonomic/CV Drugs — Flashcards

Flashcard 2331: What antiarrhythmic drug class does phenytoin belong to? _____

Answer: Class IB antiarrhythmics (anti-epileptic but has class IB properties)

Flashcard 2332: What effect do class I antiarrhythmics have on the action potentials of the SA and AV nodes?_____

Answer: No effect (only affects Na+-dependent action potentials)

Flashcard 2333: What drug is used to treat the secretory diarrhea associated with VIPoma and carcinoid syndrome?

Answer: Octreotide (a somatostatin analog)

Flashcard 2334: Which antitumor monoclonal antibody can treat rheumatoid arthritis?_____

Answer: Rituximab

Flashcard 2335: _____ is a gout drug that can cause anaphylaxis

Answer: Pegloticase

Flashcard 2336: Tacrolimus use is associated with _____-glycemia

Answer: hyper

Extra: Tacrolimus (and Cyclosporine/Corticosteroids) are immunosuppressants commonly associated with hyperglycemia (post-transplant diabetes mellitus). In contrast, Mycophenolate mofetil is considered "diabetes-sparing" and "renal-sparing." Its primary side effects include GI distress (diarrhea) and bone marrow suppression (leukopenia).

Flashcard 2337: Verapamil and diltiazem are both examples of _____ Ca2+ channel blockers

Answer: non-dihydropyridine

Flashcard 2338: Beta-blockers can cause _____ in men as an adverse effect

Answer: Impotence

Flashcard 2339: Glucocorticoids can cause atrophy of the _____ layer of the skin

Answer: dermal

Flashcard 2340: Nitrates _____ myocardial oxygen requirements

Answer: reduce