Autonomic/CV Drugs — Flashcards

Flashcard 2131: Allopurinol can result in _____-philia

Answer: eosino

Flashcard 2132: What is the effect of corticosteroids on eosinophil levels? _____

Answer: Decreased (eosinopenia)

Flashcard 2133: Sunitinib and sorafenib are associated with an increased risk of _____

Answer: hemorrhage and hyperkeratosis (hand-foot skin reaction)

Extra: Sunitinib and sorafenib are multi-kinase inhibitors (targeting VEGFR, PDGFR, and c-KIT). High-yield side effects include hypertension, hemorrhage, and hyperkeratotic skin reactions (hand-foot syndrome). Note: Sunitinib is also associated with a yellow skin discoloration and hair depigmentation.

Flashcard 2134: Which kinase inhibitor can be used to treat non-small cell lung cancer (NSCLC) with EGFR mutations?

Answer: Erlotinib

Flashcard 2135: benzodiazepines (e.g. midazolam) may be used to create a state of _____ for minor procedures and surgeries (e.g. colonoscopy, endoscopy)

Answer: conscious sedation

Flashcard 2136: Suvorexant is contraindicated in patients with _____

Answer: narcolepsy

Flashcard 2137: Is codeine by itself bioactive?_____

Answer: No

Flashcard 2138: Amylin analogues (e.g. pramlintide) decrease _____ secretion

Answer: glucagon

Flashcard 2139: Can PDE inhibitors reduce symptoms of claudication in peripheral artery disease? _____

Answer: Yes (e.g. cilostazol)

Flashcard 2140: Which classes of diuretics (2) are characterized by increased urine K+? _____

Answer: Loop and thiazide diuretics