Autonomic/CV Drugs — Flashcards

Flashcard 1721: Cocaine and amphetamine intoxication cause pupillary _____

Answer: dilation

Flashcard 1722: Alprostadil and Misoprostol are analogues of _____

Answer: PGE1

Extra: • **PGE1 analogues**: Alprostadil, Misoprostol, Gemeprost, Lubiprostone • **PGE2 analogues**: Dinoprostone • **PGF2α analogues**: Dinoprost, Carboprost, Latanoprost, Bimatoprost • **PGI2 (Prostacyclin) analogues**: Epoprostenol, Iloprost, Treprostinil

Flashcard 1723: Labetalol causes vaso-_____

Answer: dilation

Flashcard 1724: Which thioamide is contraindicated in the first trimester of pregnancy?_____

Answer: Methimazole, so need to use PTU

Flashcard 1725: How do sulfonylurea drugs (e.g., tolbutamide, glyburide) cause increased insulin secretion?

Answer: By closing the ATP-dependent K+ channels, causing depolarization and subsequent insulin release

Flashcard 1726: Class III antiarrhythmics can restore and maintain normal sinus rhythm in _____ fibrillation and flutter

Answer: atrial

Flashcard 1727: Oral bisphosphonates may cause _____ side effects

Answer: upper GI

Flashcard 1728: _____ is a T4 hormone analog used to treat hypothyroidism and myxedema.

Answer: Levothyroxine

Flashcard 1729: Which form(s) of cyclooxygenase synthesize prostaglandins that increase pain sensitivity? _____

Answer: COX-2

Flashcard 1730: Decreased cAMP as a result of class II antiarrhythmics (beta-blockers) leads to the closure of membrane _____ channels

Answer: Ca2+