Autonomic/CV Drugs — Flashcards

Flashcard 1711: Acetazolamide primarily prevents reabsorption of _____

Answer: HCO3-

Flashcard 1712: Inhaled anesthetics with _____ arteriovenous gradient have a slower onset of action

Answer: higher

Flashcard 1713: Colchicine is used to treat _____ gout

Answer: acute (acute or chronic?)

Flashcard 1714: _____ is a thioamide that is NOT contraindicated in the first trimester of pregnancy.

Answer: Propylthiouracil

Flashcard 1715: Selegiline and rasagiline may _____ the adverse effects of levodopa

Answer: exacerbate

Flashcard 1716: What class of autonomic drugs are contraindicated in cocaine toxicity? _____

Answer: Beta-blockers

Extra: Pure beta-blockers are contraindicated in cocaine toxicity due to the risk of **unopposed alpha-stimulation**. Blocking $\beta_2$-mediated vasodilation while $\alpha_1$-mediated vasoconstriction remains active can lead to severe hypertension and coronary artery vasoconstriction.

Flashcard 1717: Is eszopiclone (nonbenzodiazepine hypnotic) useful for sleep onset or sleep maintenance? _____

Answer: Both

Flashcard 1718: Propofol causes profound vaso-_____ of arteries and veins

Answer: dilation

Flashcard 1719: Decreased cAMP as a result of class II antiarrhythmics (beta-blockers) leads to the closure of membrane _____ channels

Answer: Ca2+

Flashcard 1720: Oral bisphosphonates may cause _____ side effects

Answer: upper GI