Autonomic/CV Drugs — Flashcards

Flashcard 1701: Alprostadil and Misoprostol are analogues of _____

Answer: PGE1

Extra: • **PGE1 analogues**: Alprostadil, Misoprostol, Gemeprost, Lubiprostone • **PGE2 analogues**: Dinoprostone • **PGF2α analogues**: Dinoprost, Carboprost, Latanoprost, Bimatoprost • **PGI2 (Prostacyclin) analogues**: Epoprostenol, Iloprost, Treprostinil

Flashcard 1702: What is the effect of M2 muscarinic agonists on heart rate? _____

Answer: Decreased HR (SA node)

Flashcard 1703: Cocaine and amphetamine intoxication cause pupillary _____

Answer: dilation

Flashcard 1704: Labetalol causes vaso-_____

Answer: dilation

Flashcard 1705: Which thioamide is contraindicated in the first trimester of pregnancy?_____

Answer: Methimazole, so need to use PTU

Flashcard 1706: Which form(s) of cyclooxygenase synthesize prostaglandins that increase pain sensitivity? _____

Answer: COX-2

Flashcard 1707: Oral bisphosphonates may cause _____ side effects

Answer: upper GI

Flashcard 1708: Class III antiarrhythmics can restore and maintain normal sinus rhythm in _____ fibrillation and flutter

Answer: atrial

Flashcard 1709: _____ is a long-acting partial μ-opioid agonist used to attenuate opioid withdrawal symptoms.

Answer: Buprenorphine

Flashcard 1710: Phase _____ of clinical trials confirms efficacy compared to the standard of care, as well as adverse effects

Answer: III