Autonomic/CV Drugs — Flashcards

Flashcard 1691: Capsaicin causes excessive activation of _____, resulting in defunctionalization of nociceptive nerve fibers

Answer: TRPV1

Flashcard 1692: What is the clinical use for butorphanol? _____

Answer: Severe pain relief (e.g. migraine, labor)

Flashcard 1693: What drug class do enoxaparin and dalteparin belong to? _____

Answer: Low molecular weight heparin (LMWH)

Flashcard 1694: Trazodone is a _____ histamine receptor antagonist

Answer: H1

Flashcard 1695: Binding of ADP to the P2Y12 receptor promotes optimal exposure of the _____ receptor on platelets

Answer: GPIIb/IIIa

Flashcard 1696: Loperamide and diphenoxylate are μ-opioid agonists that can be used as anti-_____

Answer: diarrheals

Flashcard 1697: The _____-opioid receptor mediates most of the clinical and adverse effects

Answer: Mu (μ)

Extra: Mu-opioid receptors are the primary mediators of the clinical effects (analgesia) and the majority of adverse effects (respiratory depression, constipation, and euphoria/addiction) associated with opioid drugs.

Flashcard 1698: Ifosfamide can cause a generalized reabsorptive defect in the _____ tubule

Answer: proximal convoluted

Flashcard 1699: Which calcineurin inhibitor binds to FK506 binding protein (FKBP)? _____

Answer: Tacrolimus (FK506)

Flashcard 1700: Does buspirone cause sedation as an adverse effect? _____

Answer: No