Autonomic/CV Drugs — Flashcards

Flashcard 1681: Capsaicin causes excessive activation of _____, resulting in defunctionalization of nociceptive nerve fibers

Answer: TRPV1

Flashcard 1682: Which NSAID is used as a tocolytic?_____

Answer: Indomethacin

Flashcard 1683: In _____ order kinetics, the rate of reaction is constant

Answer: zero

Flashcard 1684: What congenital heart defect is associated with lithium exposure in utero? _____

Answer: Ebstein anomaly

Flashcard 1685: Binding of ADP to the P2Y12 receptor promotes optimal exposure of the _____ receptor on platelets

Answer: GPIIb/IIIa

Flashcard 1686: COX-_____ is inducible by inflammation

Answer: 2

Flashcard 1687: Inhaled anesthetics with lower solubility in blood have a _____ recovery

Answer: faster

Flashcard 1688: The _____-opioid receptor mediates most of the clinical and adverse effects

Answer: Mu (μ)

Extra: Mu-opioid receptors are the primary mediators of the clinical effects (analgesia) and the majority of adverse effects (respiratory depression, constipation, and euphoria/addiction) associated with opioid drugs.

Flashcard 1689: Which reaction to monoclonal antibodies includes skin rash, fever, and arthralgias?_____

Answer: Serum sickness

Flashcard 1690: Ifosfamide can cause a generalized reabsorptive defect in the _____ tubule

Answer: proximal convoluted