Autonomic/CV Drugs — Flashcards

Flashcard 1671: What drug class does ethacrynic acid belong to?_____

Answer: Loop diuretics

Flashcard 1672: Treatment of a patent ductus arteriosus involves _____, which decreases PGE, resulting in PDA closure

Answer: indomethacin

Flashcard 1673: Which reaction to monoclonal antibodies includes skin rash, fever, and arthralgias?_____

Answer: Serum sickness

Flashcard 1674: Binding of ADP to the P2Y12 receptor promotes optimal exposure of the _____ receptor on platelets

Answer: GPIIb/IIIa

Flashcard 1675: COX-_____ is inducible by inflammation

Answer: 2

Flashcard 1676: Which calcineurin inhibitor binds to FK506 binding protein (FKBP)? _____

Answer: Tacrolimus (FK506)

Flashcard 1677: The _____-opioid receptor mediates most of the clinical and adverse effects

Answer: Mu (μ)

Extra: Mu-opioid receptors are the primary mediators of the clinical effects (analgesia) and the majority of adverse effects (respiratory depression, constipation, and euphoria/addiction) associated with opioid drugs.

Flashcard 1678: Which NSAID is used as a tocolytic?_____

Answer: Indomethacin

Flashcard 1679: In _____ order kinetics, the rate of reaction is constant

Answer: zero

Flashcard 1680: What congenital heart defect is associated with lithium exposure in utero? _____

Answer: Ebstein anomaly