Autonomic/CV Drugs — Flashcards

Flashcard 1671: In addition to beta-blockers, essential tremor may also be treated with _____

Answer: primidone (a barbiturate)

Flashcard 1672: What is the effect of oral contraceptives on coagulability? _____

Answer: Increases coagulability

Flashcard 1673: Digoxin is _____ in patients with significant SA or AV block

Answer: contraindicated

Flashcard 1674: Acetazolamide is a _____ drug and thus may cause adverse reactions in allergic patients

Answer: sulfa

Flashcard 1675: What type of nerve fiber, myelinated or unmyelinated, is affected first by local anesthetics? _____

Answer: Myelinated fibers

Flashcard 1676: One treatment for cyanide poisoning is vitamin _____ which may bind cyanide

Answer: (hydroxycobalamin) B12

Flashcard 1677: Trazodone is a _____ histamine receptor antagonist

Answer: H1

Flashcard 1678: What is the mechanism by which combined contraceptives (progestins + estradiol) act as a contraceptive? _____

Answer: Inhibit ovulation

Flashcard 1679: Which calcineurin inhibitor binds to FK506 binding protein (FKBP)? _____

Answer: Tacrolimus (FK506)

Flashcard 1680: The _____-opioid receptor mediates most of the clinical and adverse effects

Answer: Mu (μ)

Extra: Mu-opioid receptors are the primary mediators of the clinical effects (analgesia) and the majority of adverse effects (respiratory depression, constipation, and euphoria/addiction) associated with opioid drugs.