Autonomic/CV Drugs — Flashcards

Flashcard 1661: What enzyme is blocked by the immunosuppressant mycophenolate mofetil?_____

Answer: IMP dehydrogenase

Flashcard 1662: Alprazolam, Lorazepam, and Temazepam are benzodiazepines that have _____ half lifes

Answer: intermediate

Flashcard 1663: The _____-opioid receptor mediates most of the clinical and adverse effects

Answer: Mu (μ)

Extra: Mu-opioid receptors are the primary mediators of the clinical effects (analgesia) and the majority of adverse effects (respiratory depression, constipation, and euphoria/addiction) associated with opioid drugs.

Flashcard 1664: Which calcineurin inhibitor binds to FK506 binding protein (FKBP)? _____

Answer: Tacrolimus (FK506)

Flashcard 1665: Thiazolidinedione-induced fluid retention can exacerbate _____

Answer: heart failure

Flashcard 1666: Leuprolide is a GnRH analog with _____ properties when used in a pulsatile fashion

Answer: agonist

Flashcard 1667: What drug class does ethacrynic acid belong to?_____

Answer: Loop diuretics

Flashcard 1668: Which reaction to monoclonal antibodies includes skin rash, fever, and arthralgias?_____

Answer: Serum sickness

Flashcard 1669: Inhaled anesthetics with lower solubility in blood have a _____ recovery

Answer: faster

Flashcard 1670: COX-_____ is inducible by inflammation

Answer: 2