Autonomic/CV Drugs — Flashcards

Flashcard 1661: Reversal of thrombolytic therapy may involve platelet transfusions or _____ corrections (e.g. FFP, cryoprecipitate, PCC)

Answer: factor

Flashcard 1662: Which MAO inhibitors (2) are selective MAO-B inhibitors? _____

Answer: Selegiline and rasagiline

Flashcard 1663: Evolocumab and alirocumab are lipid-lowering agents that inhibit _____

Answer: PCSK9 (what enzyme?)

Flashcard 1664: Trazodone is a _____ histamine receptor antagonist

Answer: H1

Flashcard 1665: Binding of ADP to the P2Y12 receptor promotes optimal exposure of the _____ receptor on platelets

Answer: GPIIb/IIIa

Flashcard 1666: The _____-opioid receptor mediates most of the clinical and adverse effects

Answer: Mu (μ)

Extra: Mu-opioid receptors are the primary mediators of the clinical effects (analgesia) and the majority of adverse effects (respiratory depression, constipation, and euphoria/addiction) associated with opioid drugs.

Flashcard 1667: Which NSAID is used as a tocolytic?_____

Answer: Indomethacin

Flashcard 1668: Do glucocorticoids cause an increase or decrease in eosinophils?_____

Answer: Decrease

Flashcard 1669: Loperamide and diphenoxylate are μ-opioid agonists that can be used as anti-_____

Answer: diarrheals

Flashcard 1670: What phase of drug metabolism includes methylation, glucuronidation, acetylation, and sulfation (i.e. conjugation)? _____

Answer: Phase II