Autonomic/CV Drugs — Flashcards

Flashcard 1591: Is protamine sulfate effective at reversing the effects of LMWH and fondaparinux? _____

Answer: LMWH: Partially reversed; Fondaparinux: Not reversed

Extra: Protamine sulfate is the specific antagonist for Unfractionated Heparin (UFH). It only partially reverses LMWH (approximately 60-75%) and has no effect on Fondaparinux.

Flashcard 1592: What drug is used to reverse the effects of dabigatran? _____

Answer: Idarucizumab

Flashcard 1593: Rituximab is indicated for _____ purpura

Answer: immune thrombocytopenic

Flashcard 1594: Gabapentin is a _____ spectrum anti-epileptic

Answer: narrow

Flashcard 1595: Which class of anti-platelet drugs may cause TTP as an adverse effect?_____

Answer: ADP receptor inhibitors

Flashcard 1596: Patients with polycythemia vera may take low-dose _____ to decrease risk of thrombosis

Answer: aspirin

Flashcard 1597: Lithium has a narrow _____

Answer: therapeutic index

Flashcard 1598: Paroxysmal nocturnal hemoglobinuria may be treated with _____, which is a terminal complement inhibitor

Answer: eculizumab

Flashcard 1599: What drug class does bivalirudin belong to? _____

Answer: Direct thrombin inhibitor

Flashcard 1600: Valproic acid _____ levels of GABA in the CNS via inhibition of GABA transaminase

Answer: increases