Antimicrobials — Flashcards

Flashcard 591: Which antimalarial can result in retinopathy?_____

Answer: Chloroquine

Flashcard 592: Palbociclib is a small molecular inhibitor of the _____ enzymes

Answer: CDK 4/6

Flashcard 593: Which chemotherapeutic drug is known to cause acute tubular necrosis?_____

Answer: Cisplatin

Flashcard 594: What is the effect of glucocorticoids on blood lymphocyte levels? _____

Answer: Decreased (especially T-helper cells)

Flashcard 595: Which types of vaccine induce a relatively weak immune response? _____

Answer: Inactivated/killed vaccines and Subunit vaccine (2)

Flashcard 596: What is the formula for calculating drug clearance (CL)?

Answer: CL = Rate of elimination / Plasma drug concentration

Extra: CL = Vd × Ke = (0.693 × Vd) / t1/2

Flashcard 597: Which form of immune hemolytic anemia (IgG or IgM) may be caused by drugs? _____

Answer: IgG

Flashcard 598: Which of the antimetabolite chemo drugs can cause neurotoxicity?_____

Answer: Cladribine

Flashcard 599: Which chemotherapeutic drug is associated with pancreatitis?_____

Answer: Azathioprine/6-MP

Flashcard 600: What class of drugs does ifosfamide belong to?_____

Answer: Alkylating agents (cytotoxic chemo)