Antimicrobials — Flashcards

Flashcard 601: What osmotic laxative is used to treat hepatic encephalopathy? _____

Answer: Lactulose

Flashcard 602: Panobinostat and Vorinostat are antineoplastics that are nonselective _____ Inhibitors

Answer: Histone Deacetylase [HDAC]

Flashcard 603: Examples of the beers criteria include drugs that increase the risk of _____ infections (PPI's)

Answer: C. difficile

Flashcard 604: What is the formula for calculating drug clearance (CL)?

Answer: CL = Rate of elimination / Plasma drug concentration

Extra: CL = Vd × Ke = (0.693 × Vd) / t1/2

Flashcard 605: What class of drugs does ifosfamide belong to?_____

Answer: Alkylating agents (cytotoxic chemo)

Flashcard 606: Which chemotherapeutic drug is associated with pancreatitis?_____

Answer: Azathioprine/6-MP

Flashcard 607: Cyclophosphamide can result in _____-suppression with resultant -cytopenias

Answer: myelo

Flashcard 608: Monoclonal antibodies can sometimes cause a(n) _____ immediately upon IV administration

Answer: infusion reaction

Flashcard 609: Which drug elimination is characterized by an exponential curve?_____

Answer: First-order elimination

Flashcard 610: Palbociclib prevents cell cycle progression past the _____ restriction point

Answer: G1-->S