Antimicrobial pharmacokinetics/pharmacodynamics — Flashcards

Trimethoprim-Sulfamethoxazole (TMP-SMX) are used for prophylaxis and treatment of _____ pneumonia

One adverse effect of proton pump inhibitors (PPIs) is increased risk for _____ infection (2-3x increased risk)

Examples of the beers criteria include drugs that increase the risk of _____ infections (PPI's)

Which of the antitumor antibiotics (3) are associated with myelosuppression?_____

Which gout drug prevents renal excretion of drugs (ie: penicillin; cidofovir)?_____

Which type of drug elimination is characterized by a constant rate of elimination (resulting in a straight-line decrease in plasma concentration over time)?

Doxorubicin has a _____ range of chemotherapeutic uses and is commonly used in clinical practice

What formula is used to estimate volume of distribution (Vd)?_____

Which anti-epileptic is eliminated via zero order kinetics? _____

What is the common treatment for all rickettsial diseases?