Anthelmintics — Flashcards

Flashcard 1: What is the treatment for intestinal Taenia solium infection?_____

Answer: Praziquantel

Flashcard 2: What is the treatment for Clonorchis sinensis?_____

Answer: Praziquantel

Flashcard 3: Trichuris trichiura (whipworm) is treated with _____

Answer: albendazole

Flashcard 4: Trichinella spiralis is treated with _____

Answer: albendazole

Flashcard 5: What is the treatment for Schistosoma spp.?_____

Answer: Praziquantel

Flashcard 6: What is the common treatment for all rickettsial diseases?

Answer: doxycycline

Flashcard 7: What are the two most characteristic toxicities associated with aminoglycosides?

Answer: Ototoxicity (Cranial Nerve VIII damage) and Nephrotoxicity

Flashcard 8: tetracyclines

Answer: discolored teeth

Flashcard 9: What is the mechanism of action of Antimycin A?

Answer: Inhibits Complex III of the Electron Transport Chain (ETC)

Extra: Antimycin A blocks the transfer of electrons from cytochrome b to cytochrome c1, effectively inhibiting the Electron Transport Chain and oxidative phosphorylation.

Flashcard 10: What is the mechanism of action of Cyanide?

Answer: Inhibits Cytochrome c oxidase (Complex IV) of the Electron Transport Chain, stopping oxidative phosphorylation.

Extra: Cyanide binds to the ferric (Fe3+) iron in cytochrome a3, preventing the final transfer of electrons to oxygen. Treatment: Nitrites (to create methemoglobin), Thiosulfate, or Hydroxocobalamin.