Antimicrobials US Medical PG Flashcards - Medical Study Cards
Master Antimicrobials with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
Antimicrobials Flashcard Deck - 10 Cards
Flashcard 241: Platinum analogs are associated with _____ and _____
Answer: nephrotoxicity
Extra: Platinum analogs include cisplatin, carboplatin, and oxaliplatin.
Note: Amifostine can be used to prevent cisplatin-induced nephrotoxicity.
Flashcard 242: Esophagitis may occur with medications such as _____, tetracyclines, NSAIDs, iron, and potassium chloride
Answer: bisphosphonates
Extra: Watch associated Bootcamp video [https://app.bootcamp.com/med-school/gastroenterology/videos/esophageal-and-gastric-pathology?index=2]
https://onlinemeded.org/spa/gastroenterology/esophagus/acquire?ref=anki
Flashcard 243: Pyrimethamine + Sulfadiazine is the 1st line treatment for _____
Answer: Toxoplasmosis
Flashcard 244: Actinomycin D (aka Dactinomycin) is an antineoplastic antibiotic that works by preventing _____ through the process of DNA intercalation
Answer: transcription
Extra:
https://onlinemeded.org?ref=anki
Flashcard 245: Cladribine is activated primarily in _____ and is resistant to degradation by adenosine deaminase (ADA).
Answer: lymphocytes
Extra: Cladribine is a purine analog that is phosphorylated to its active form by deoxycytidine kinase. Unlike adenosine, it is resistant to degradation by adenosine deaminase (ADA), leading to high intracellular concentrations and toxicity in lymphocytes.
Note: Pentostatin is the drug that actually inhibits ADA.
Flashcard 246: Lung cancers with a EML4-ALK fusion protein are typically EGFR _____ / KRAS _____
*bonus: treat with..?
Answer: negative
Extra: Watch associated Bootcamp video [https://app.bootcamp.com/med-school/pulmonology/videos/lung-cancer?index=6]
https://onlinemeded.org/spa/pulmonology/lung-cancer/acquire?ref=anki
Flashcard 247: What class of antimicrobials are the following drugs?
- Azithromycin
- Clarithromycin
- Erythromycin
_____
Answer: Macrolides
Extra: Macrolides typically end in the suffix **-thromycin**. Note that Fidaxomicin is a unique macrolide used for *C. difficile*.
Flashcard 248: Anthracyclines are used to treat _____ blood cell neoplasias
Answer: white
Extra:
Watch Bleomycin, doxorubicin, daunorubicin, actinomycin D [https://dashboard.sketchy.com/study/medical/courses/medical-pharmacology/units/medical-pharmacology-antineoplastics/videos/medical-pharmacology-antineoplastics-dna-and-cellular-division-bleomycin-doxorubicin-daunorubicin-actinomycin-d?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
https://onlinemeded.org?ref=anki
Flashcard 249: Proteasomal inhibitors work best in cancers that mark _____ proteins to be targeted for degradation too quickly
Answer: pro-apoptotic
Extra: #REF!
https://onlinemeded.org?ref=anki
Flashcard 250: Which enzyme is inhibited by etoposide?
_____
Answer: topoisomerase II
Extra:
Watch DNA Replication [https://dashboard.sketchy.com/study/medical/courses/medical-biochemistry/units/medical-biochemistry-molecular-biology/videos/medical-biochemistry-molecular-biology-dna-dna-replication?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
Watch Etoposide, teniposide, topotecan, irinotecan [https://dashboard.sketchy.com/study/medical/courses/medical-biochemistry/units/medical-biochemistry-molecular-biology/videos/medical-biochemistry-molecular-biology-dna-dna-replication?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]Watch associated Bootcamp video [https://app.bootcamp.com/med-school/genetics/videos/dna-replication-transcription-and-translation?index=2]
https://onlinemeded.org?ref=anki
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