Central Nervous System Pharmacology — Flashcards

Flashcard 181: Which anti-epileptic acts by blocking voltage-gated Na+ channels and T-type calcium channels and also has carbonic anhydrase inhibiting activity?

Answer: Zonisamide

Flashcard 182: The most common side effect of amantadine is minor _____ toxicity

Answer: CNS

Flashcard 183: Betahistine is a H1 receptor _____ used in Meniere's disease

Answer: agonist

Flashcard 184: Which drugs are pure opioid antagonists?_____

Answer: Naloxone, naltrexone and Nalmefene (3)

Flashcard 185: Mechanism of action of MgSO4: Potentiation of _____ action

Answer: adenosine (neurotransmitter)

Flashcard 186: _____ is the drug of choice for infantile spasms associated with tuberous sclerosis.

Answer: Vigabatrin

Flashcard 187: Which amide local anesthetic has the fastest onset of action?

Answer: Mepivacaine

Flashcard 188: What is the botanical name of the plant from which cocaine is derived?

Answer: Erythroxylum coca

Extra: The plant Erythroxylum coca (family Erythroxylaceae) is the primary source of the alkaloid cocaine, which acts as a potent CNS stimulant and local anesthetic.

Flashcard 189: Use of reserpine results in low levels of _____

Answer: Dopamine, norepinephrine, and serotonin (monoamines)

Flashcard 190: Valproate is _____ used as a first line drug in the treatment of focal seizures with intact awareness

Answer: not