Central Nervous System Pharmacology — Flashcards

Flashcard 141: N2O is NMDA receptor _____ in the brain

Answer: antagonist

Flashcard 142: _____ are a drug of abuse least likely to be associated with seizures

Answer: Cannabinoids

Flashcard 143: Which -vaptan is associated with mood and nociception disturbances as an adverse effect?

Answer: Nelivaptan

Flashcard 144: Which form of cocaine can be smoked?

Answer: Freebase (Crack)

Extra: Cocaine hydrochloride (the salt form) decomposes when heated and is typically snorted or injected. The freebase form (crack) has a lower melting point, which allows it to be vaporized and smoked. (Note: Coca paste, which contains cocaine sulfate, is also smoked, but Freebase is the standard pharmacological answer for the smokable form).

Flashcard 145: _____ is the most potent, most toxic and longest acting local anaesthetic agent

Answer: Dibucaine

Flashcard 146: _____ (GHB) also called liquid ecstasy is a naturally-occurring neurotransmitter, which acts as a CNS depressant

Answer: Gamma-hydroxybutyrate

Flashcard 147: _____ is an opioid antagonist, with properties similar to those of naloxone.

Answer: Levallorphan

Flashcard 148: Does Strychnine affect brain receptors?_____

Answer: No

Flashcard 149: 5HT1A receptor _____ has been found to reduce food intake and hence reduce body weight.

Answer: antagonists

Flashcard 150: Perampanel is associated with the side effect of _____

Answer: suicidal ideation