Cholinergic/Adrenergic drugs — Flashcards

Flashcard 51: Cocaine exerts its effects via inhibition of the _____ and _____ transporters (reuptake inhibitor)

Answer: NET

Extra: Sketchy Pharmacology: Autonomics (Indirect Sympathomimetics)

Flashcard 52: What G-protein is the M2 muscarinic receptor coupled to? _____

Answer: Gi

Extra: Sketchy Pharmacology: Autonomics (Cholinomimetics)

Flashcard 53: Aminoglycosides can impact the neuromuscular junction, primarily inhibiting _____ _____

Answer: presynaptic

Extra: Aminoglycosides inhibit pre-synaptic ACh release (primary mechanism) and also reduce post-synaptic sensitivity to ACh. This neuromuscular blockade can lead to respiratory depression and is especially dangerous in patients with Myasthenia Gravis.

Flashcard 54: β-Blockers are used to treat _____ by blocking the hyperadrenergic symptoms

Answer: Thyrotoxicosis (thyroid storm)

Flashcard 55: What drug class does vortioxetine belong to? _____

Answer: Atypical antidepressants

Extra: First Aid Pharmacology: Neuro/Psych

Flashcard 56: Parathion, malathion, and echothiophate are all examples of _____

Answer: organophosphates

Extra: Sketchy Pharmacology: Autonomics

Flashcard 57: Clostridium botulinum toxin is associated with the 5 Ds: 1. _____ 2. Dysphonia (anti-cholinergic) 3. Dysphagia (anti-cholinergic) 4. Dry mouth (anti-muscarinic) 5. myDriasis (anti-muscarinic)

Answer: Diplopia (anti-cholinergic)

Flashcard 58: Phase _____ of succinylcholine-induced neuromuscular blockade is characterized as repolarized but blocked

Answer: II

Extra: First Aid Pharmacology: Neuro/Psych #REF!

Flashcard 59: Compared to typical antipsychotics, atypical antipsychotics cause _____ anti-cholinergic side effects

Answer: less

Extra: Sketchy Pharmacology: Neuro/Psych

Flashcard 60: Which anti-muscarinic (tiotropium or ipratropium) is longer-acting? _____

Answer: Tiotropium

Extra: Sketchy Pharmacology: Autonomics (Antimuscarinics)