Autonomic/CV Drugs — Flashcards

Flashcard 981: Because Sorafenib and Sunitinib target the Vascular Endothelial Growth Factor receptor, patients are at increased risk of _____

Answer: hemorrhage

Flashcard 982: Adverse effects of **vilazodone** include nausea, diarrhea, and (to a lesser extent than TCAs/SSRIs) anti-_____ effects and weight gain.

Answer: cholinergic

Extra: Vilazodone is a SPARI (Serotonin Partial Agonist and Reuptake Inhibitor). It is notably associated with GI upset (diarrhea) but has a lower incidence of sexual dysfunction and weight gain compared to most SSRIs.

Flashcard 983: Mirabegron is a sympathomimetic that _____ β3 receptors

Answer: stimulates

Extra: First Aid Pharmacology: Autonomics

Flashcard 984: What is the effect of thiazolidinediones on the differentiation and number of adipocytes? _____

Answer: Increased

Extra: Sketchy Pharmacology: Endocrine (diabetes)

Flashcard 985: Adverse effects associated with levetiracetam use include _____ and neuropsychiatric symptoms (e.g. behavioral change)

Answer: somnolence

Extra: Sketchy Pharmacology: Neuro/Psych

Flashcard 986: Guaifenesin is a(n) expectorant that _____ respiratory secretions

Answer: thins

Extra: First Aid Pharmacology: Respiratory

Flashcard 987: Mannitol may be used clinically for drug _____

Answer: overdose

Extra: First Aid Pharmacology: Renal (Diuretics)

Flashcard 988: _____ may be used in the treatment of primary or secondary hyperparathyroidism by increasing sensitivity to Ca2+-sensing receptors

Answer: Cinacalcet

Extra: First Aid Pharmacology: Endocrine

Flashcard 989: Because iloprost and epoprostenol are potent vasodilators, these may cause symptoms of _____, headache, and hypotension

Answer: cutaneous flushing

Flashcard 990: Misoprostol is a synthetic analog of _____

Answer: PGE1

Extra: Sketchy Pharmacology: GI