Autonomic/CV Drugs — Flashcards

Flashcard 971: Sildenafil inhibits _____ and prolongs the vasodilatory effect of nitric oxide

Answer: PDE-5

Extra: First Aid Pharmacology: Respiratory

Flashcard 972: Do most NSAIDs inhibit COX-1 or COX-2? _____

Answer: Both :)

Flashcard 973: What is the clinical use for orlistat? _____

Answer: Weight loss

Extra: First Aid Pharmacology: GI (Weight Loss)

Flashcard 974: What classes of diuretics are characterized by decreased blood pH (acidemia)? _____

Answer: Carbonic anhydrase inhibitors, K+ sparing diuretics

Extra: First Aid Pharmacology: Renal (Diuretics)

Flashcard 975: Inhaled anesthetics with _____ arteriovenous gradient have a slower onset of action

Answer: higher

Flashcard 976: Does chronic opiate use lead to tolerance? _____

Answer: Yes

Extra: Sketchy Pharmacology: Neuro/Psych

Flashcard 977: Desmopressin increases release of _____ from Weibel-Palade bodies

Answer: vWF

Extra: * Weibel-Palade bodies in endothelial cells

Flashcard 978: What class of drugs acts by closing K+ channels in pancreatic β cells, causing increased insulin secretion? _____

Answer: Sulfonylurea drugs (e.g. tolbutamide, glyburide)

Flashcard 979: Because Her2/Neu is expressed on the _____, Trastuzumab can cause _____ failure

Answer: Heart

Flashcard 980: Isoproterenol causes _____ HR and contractility

Answer: increased

Extra: Sketchy Pharmacology: Autonomics (Sympathomimetics)