Autonomic/CV Drugs — Flashcards

Flashcard 831: Taxane can affect rapidly dividing cells like follicular hair cells, resulting in _____

Answer: alopecia

Extra: Sketchy Pharmacology: Antineoplastics - Me Taxane, You Christine

Flashcard 832: Benzodiazepines exert their effects via binding to an allosteric site on the _____ receptor

Answer: GABAA

Extra: Sketchy Pharmacology: Neuro/Psych

Flashcard 833: What drugs increase risk of progressive multifocal leukoencephalopathy? _____

Answer: Natalizumab; Rituximab

Flashcard 834: _____ interstitial nephritis is typically seen with patients who've been taking NSAIDs for a long time

Answer: Chronic

Flashcard 835: What compartment is the majority of a drug with medium Vd found in? _____

Answer: Extracellular fluid

Flashcard 836: Can PDE inhibitors reduce symptoms of claudication in peripheral artery disease? _____

Answer: Yes (e.g. cilostazol)

Flashcard 837: What is the effect of glucocorticoids on production of phospholipase A2? _____

Answer: Decreased (inhibition)

Extra: Sketchy Pharmacology: Thyroid, Pituitary, & Adrenal

Flashcard 838: Atezolizumab, durvalumab, and avelumab are checkpoint inhibitors that bind to _____ on tumor cells

Answer: PD-L1

Flashcard 839: Carbamazepine is a(n) inducer of _____ and thus may have many drug interactions

Answer: cytochrome P450

Extra: Sketchy Pharmacology: Neuro/Psych

Flashcard 840: Class IA antiarrhythmics can cause _____ prolongation which precipitates torsades de pointes

Answer: QT interval

Extra: Sketchy Pharmacology: Cardiovascular (Antiarrhythmics)