Autonomic/CV Drugs — Flashcards

Flashcard 791: Valproic acid exerts its effects by increasing _____ channel inactivation and inhibiting GABA transaminase

Answer: Na+

Extra: Sketchy Pharmacology: Neuro/Psych

Flashcard 792: What drug class do enoxaparin and dalteparin belong to? _____

Answer: Low molecular weight heparin (LMWH)

Flashcard 793: Loop diuretics attach to the Cl--binding site of the _____ cotransporter

Answer: Na+-K+-2Cl-

Flashcard 794: Which kinase inhibitor can be used to treat malignant melanoma due to V600E BRAF kinase overexpression? _____

Answer: Vemurafenib

Flashcard 795: Terbutaline is a selective _____ agonist that treats bronchoconstriction in asthma

Answer: β2

Extra: Sketchy Pharmacology: Respiratory (Asthma)

Flashcard 796: Does warfarin cross the placenta? _____

Answer: Yes (lipid soluble)

Flashcard 797: What drug can bind acrolein and prevent hemorrhagic cystitis in cyclophosphamide, ifosfamide use? _____

Answer: MESNA (2-mercaptoethanesulfonate)

Flashcard 798: Chronic glucocorticoid use may cause Iatrogenic _____ syndrome

Answer: Cushing

Extra: Sketchy Pharmacology: Thyroid, Pituitary, & Adrenal

Flashcard 799: Leuprolide, Goserelin, and Buserelin are GnRH **agonists** that exhibit _____ effects when used in a **continuous** fashion.

Answer: antagonist

Extra: These drugs cause a transient initial surge in LH and FSH (flare), followed by down-regulation of GnRH receptors in the anterior pituitary, leading to decreased LH/FSH and decreased testosterone/estrogen.

Flashcard 800: What drug used to treat hyperthyroidism is associated with hepatotoxicity? _____

Answer: Propylthiouracil

Extra: First Aid Pharmacology: Endocrine