Autonomic/CV Drugs — Flashcards

Flashcard 681: What type of drug interaction occurs when the effect of substance A and B together is equal to the sum of their individual effects? _____

Answer: Additive (e.g. aspirin and acetaminophen)

Extra: Additive interaction: The combined effect of two drugs is equal to the sum of their individual effects (1 + 1 = 2). Example: Aspirin and acetaminophen.

Flashcard 682: Binding of ADP to the P2Y12 receptor promotes optimal exposure of the _____ receptor on platelets

Answer: GPIIb/IIIa

Flashcard 683: In patients with cardiovascular disease history, Bevacizumab is contraindicated due to the increased risk of _____ events

Answer: Thrombotic

Flashcard 684: _____ is a thioamide indicated in the treatment of thyroid storm (thyrotoxicosis)

Answer: Propylthiouracil

Flashcard 685: What effect do fibrates have on HDL levels? _____

Answer: Mildly increased HDL

Extra: Sketchy Pharmacology: Blood & Inflammation (Dyslipidemia drugs)

Flashcard 686: _____ is a thyroid medication that can produce an ANCA-associated vasculitis

Answer: Propylthiouracil (PTU)

Flashcard 687: What hormone analog may be used to treat VIPoma and carcinoid syndrome? _____

Answer: Octreotide (somatostatin analog)

Extra: Sketchy Pharmacology: Thyroid, Pituitary, & Adrenal

Flashcard 688: How do glucocorticoids suppress the immune response? _____

Answer: By inhibiting production of IL-2 and subsequent T-cell proliferation

Flashcard 689: Oral bisphosphonates may cause _____ side effects

Answer: upper GI

Extra: Sketchy Pharmacology: Thyroid, Pituitary, & Adrenal

Flashcard 690: _____ is a potentially lethal adverse effect associated with any drug that increases 5-HT

Answer: Serotonin syndrome

Extra: Sketchy Pharmacology: Neuro/Psych