Autonomic/CV Drugs — Flashcards

Flashcard 511: What class of diabetic drugs is associated with increased risk of fracture as a possible side effect? _____

Answer: Thiazolidinediones (glitazones)

Extra:   Sketchy Pharmacology: Endocrine (diabetes) Watch Metformin, thiazolidinediones, pramlintide, SGLT2 inhibitors [https://dashboard.sketchy.com/study/medical/courses/medical-pharmacology/units/medical-pharmacology-gi-endocrine/videos/medical-pharmacology-gi-and-endocrine-diabetes-metformin-thiazolidinediones-pramlintide-sglt2-inhibitors?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] https://onlinemeded.org/spa/surgery-general/pancreas/acquire?ref=anki 

Flashcard 512: Histamine causes _____ of bronchial smooth muscle, especially in patients with asthma (H1 receptor activation)

Answer: constriction

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Flashcard 513: The goal INR for warfarin therapy is typically between _____ - _____

Answer: 2

Extra:   Watch Warfarin [https://dashboard.sketchy.com/study/medical/courses/medical-pharmacology/units/medical-pharmacology-blood-inflammation/videos/medical-pharmacology-blood-and-inflammation-anticoagulants-and-thrombolytics-warfarin?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]Watch associated Bootcamp video [https://app.bootcamp.com/med-school/hematology-and-oncology/videos/coagulation-and-fibrinolysis?index=11] https://onlinemeded.org/spa/heme-onc/hemostasis/acquire?ref=anki 

Flashcard 514: Commonly associated drugs with DRESS syndrome include _____, carbamazepine, allopurinol, sulfonamides

Answer: phenytoin

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Flashcard 515: Pramlintide (amylin analog) is used to control the _____ glucose spike

Answer: postprandial

Extra:   Sketchy Pharmacology: Endocrine (diabetes) Watch Metformin, thiazolidinediones, pramlintide, SGLT2 inhibitors [https://dashboard.sketchy.com/study/medical/courses/medical-pharmacology/units/medical-pharmacology-gi-endocrine/videos/medical-pharmacology-gi-and-endocrine-diabetes-metformin-thiazolidinediones-pramlintide-sglt2-inhibitors?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] https://onlinemeded.org/spa/surgery-general/pancreas/acquire?ref=anki 

Flashcard 516: Adverse effects of sirolimus (rapamycin) include _____ and insulin resistance

Answer: pancytopenia

Flashcard 517: What drug class does ethacrynic acid belong to? _____

Answer: Loop diuretics

Extra:   Sketchy Pharmacology: Renal (Diuretics) Watch Loop diuretics [https://dashboard.sketchy.com/study/medical/courses/medical-pharmacology/units/medical-pharmacology-cardiovascular-renal/videos/medical-pharmacology-cardiovascular-and-renal-diuretics-loop-diuretics?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] https://onlinemeded.org/spa/cardiology/hypertension/acquire?ref=anki 

Flashcard 518: Are class IA antiarrhythmics used to treat supraventricular or ventricular arrhythmias? _____

Answer: Both :)

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Flashcard 519: Fibrates increase risk of _____ and thus should be used with caution in patients with biliary tract disease

Answer: cholesterol gallstones

Extra:   Sketchy Pharmacology: Blood & Inflammation (Dyslipidemia drugs) Watch Fibrates, niacin [https://dashboard.sketchy.com/study/medical/courses/medical-pharmacology/units/medical-pharmacology-blood-inflammation/videos/medical-pharmacology-blood-and-inflammation-dyslipidemia-drugs-fibrates-niacin?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] https://onlinemeded.org/spa/cardiac?ref=anki 

Flashcard 520: K+ sparing diuretics (e.g. spironolactone, eplerenone) are useful in the treatment of heart _____, especially in combination with loop diuretics

Answer: failure

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