Autonomic/CV Drugs — Flashcards

Flashcard 2611: Which long-acting μ-opioid receptor agonist is used to attenuate opioid withdrawal symptoms? Bonus: It is also an antagonist at which receptor?

Answer: Methadone Bonus: NMDA receptor

Flashcard 2612: Dyslipidemia drugs _____ bind bile acids in the intestinal lumen, preventing absorption and recycling to the liver

Answer: Bile acid resins (e.g. cholestyramine)

Flashcard 2613: Danazol is used to treat _____ and hereditary angioedema

Answer: endometriosis

Flashcard 2614: Phentolamine causes vaso-_____

Answer: dilation

Flashcard 2615: What is the most serious adverse effect associated with antipsychotics? _____

Answer: Neuroleptic malignant syndrome (NMS)

Flashcard 2616: Which atypical antipsychotic is a D2 partial agonist? _____

Answer: Aripiprazole

Flashcard 2617: Phenobarbital is an _____ of CYP-450

Answer: inducer

Flashcard 2618: Methotrexate has an _____ effect, hence why it is useful in the treatment of IBD, vasculitis, SLE, dermatomyositis, etc.

Answer: immunosuppressive

Flashcard 2619: Alpha-receptor antagonists may cause _____ (BP) as an adverse effect.

Answer: Orthostatic hypotension

Extra: Alpha-1 receptor antagonists (e.g., prazosin, doxazosin, terazosin) inhibit vasoconstriction, leading to a drop in blood pressure upon standing. This is often referred to as the "first-dose phenomenon."

Flashcard 2620: NSAIDs can _____ blood pressure

Answer: increase