Autonomic/CV Drugs — Flashcards

Flashcard 211: Can cortisone activate mineralocorticoid receptors? _____

Answer: No

Flashcard 212: Which test is used to follow the effects of heparin? _____

Answer: PTT

Flashcard 213: Use of Linezolid is contraindicated in patients taking drugs that increase _____ transmission

Answer: serotonergic

Flashcard 214: Sacubitril is a(n) _____ inhibitor

Answer: neprilysin

Extra: #REF!

Flashcard 215: Amiodarone, a class III antiarrhythmic, can act as a(n) _____, resulting in blue-gray skin discoloration

Answer: hapten

Extra: Sketchy Pharmacology: Cardiovascular (Antiarrhythmics)

Flashcard 216: _____ and Sulfa drugs are both known to cause drug-induced lupus (syndrome associated with anti-histone antibodies).

Answer: Etanercept

Extra: Drug-induced lupus is characterized by anti-histone antibodies and the absence of anti-dsDNA antibodies. Etanercept is a TNF-α inhibitor.

Flashcard 217: Coadministration of ACE inhibitors with _____ can precipitate acute kidney injury

Answer: NSAIDs

Extra: FA2020 UPDATE: ACE inhibitors dilate the efferent arteriole, not constrict as the image below states: Sketchy Pharmacology: Cardiovascular/Renal NSAIDs decrease afferent dilation by prostaglandins, ACE Inhibitors vasodilate efferent arteriole (overall less blood flow to kidney)

Flashcard 218: Ursodeoxycholic acid acts via increasing _____ secretion and decreasing _____ secretion/reabsorption

Answer: bile

Extra: First Aid Pharmacology: GI

Flashcard 219: Chronic levodopa use can cause an "_____ phenomenon", with periods of akinesia alternating with periods of improved mobility

Answer: on-off

Extra: Sketchy Pharmacology: Neuro/Psych

Flashcard 220: Fondaparinux is an anticoagulant that acts only on factor _____

Answer: Xa