Autonomic/CV Drugs — Flashcards

Flashcard 201: Benzodiazepines can cause _____ by downregulating GABAA receptors

Answer: tolerance

Extra:   Sketchy Pharmacology: Neuro/Psych Watch Benzodiazepines, flumazenil [https://dashboard.sketchy.com/study/medical/courses/medical-pharmacology/units/medical-pharmacology-neuro-psych/videos/medical-pharmacology-neuropsych-sedative-hypnotics-benzodiazepines-flumazenil?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]Watch associated Bootcamp video [https://app.bootcamp.com/med-school/psychiatry/videos/substance-misuse?index=6] https://onlinemeded.org?ref=anki 

Flashcard 202: Which anticoagulant has the greatest efficacy on factor IIa (thrombin)? _____

Answer: Heparin

Extra:   https://onlinemeded.org?ref=anki UWorld: 

Flashcard 203: Allopurinol is a treatment for chronic gout, as it inhibits _____

Answer: xanthine oxidase

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Flashcard 204: Phenytoin exerts its effects by blocking _____ channels

Answer: Na+

Extra:   Sketchy Pharmacology: Neuro/Psych Watch associated Bootcamp video [https://app.bootcamp.com/med-school/neurology/videos/seizures?index=11] https://onlinemeded.org/spa/pediatrics/seizures/acquire?ref=anki 

Flashcard 205: _____ is a monoclonal antibody against RANKL, useful in the treatment of osteoporosis

Answer: Denosumab

Extra:   Sketchy Pharmacology: Thyroid, Pituitary, & Adrenal Watch Bisphosphonates, raloxifene, denosumab, calcitonin [https://dashboard.sketchy.com/study/medical/courses/medical-pharmacology/units/medical-pharmacology-gi-endocrine/videos/medical-pharmacology-gi-and-endocrine-thyroid-parathyroid-and-adrenal-bisphosphonates-raloxifene-denosumab-calcitonin?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] https://onlinemeded.org/spa/immunology?ref=anki  Binds to RANKL to prevent RANKL from activating osteoclasts 

Flashcard 206: Cinacalcet is an allosteric activator of the _____ receptor on the Parathyroid Gland

Answer: Ca2+ sensing (CaSR)

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Flashcard 207: MAO inhibitors are contraindicated in patients taking _____, which is a medicinal herb with antidepressant activity

Answer: St. John's wort

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Flashcard 208: What is the mechanism of action of zileuton (asthma treatment)? _____

Answer: 5-lipoxygenase inhibitor

Extra:   Sketchy Pharmacology: Respiratory (Asthma) Watch Asthma therapy [https://dashboard.sketchy.com/study/medical/courses/medical-pharmacology/units/medical-pharmacology-smooth-muscle/videos/medical-pharmacology-smooth-muscle-allergy-and-pulmonary-asthma-therapy?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]Watch associated Bootcamp video [https://app.bootcamp.com/med-school/pulmonology/videos/obstructive-lung-disease?index=6] https://onlinemeded.org/spa/general-physiology/smooth-muscle/acquire?ref=anki 

Flashcard 209: Use of Linezolid is contraindicated in patients taking drugs that increase _____ transmission

Answer: serotonergic

Flashcard 210: What classes of antiarrhythmics are used for rhythm control in atrial fibrillation and flutter? _____

Answer: Class IC and III

Extra:  First Aid Pharmacology: Cardiovascular (Antiarrhythmics)   https://onlinemeded.org/spa/cardiac/arrhythmias/acquire?ref=anki