Autonomic/CV Drugs — Flashcards

Flashcard 2061: What D2 receptor antagonist is used to treat Huntington disease? _____

Answer: Haloperidol (typical antipsychotic)

Flashcard 2062: Organic nitrates are metabolized and release _____

Answer: nitric oxide

Flashcard 2063: Are anti-alpha-1 effects more common with high- or low-potency typical antipsychotics?

Answer: Low potency

Flashcard 2064: What effect do class III antiarrhythmics have on action potential duration?_____

Answer: Increased AP duration

Flashcard 2065: The inhaled anesthetic _____ is associated with expansion of trapped gas in a body cavity as an adverse effect

Answer: N2O

Flashcard 2066: Which calcium channel blocker is used as a tocolytic?_____

Answer: Nifedipine

Flashcard 2067: **Methotrexate** must be monitored with LFTs because chronic use increases the risk of hepatic fibrosis and _____.

Answer: cirrhosis (hepatic fibrosis)

Extra: Methotrexate is a folate antagonist (inhibits dihydrofolate reductase) used for rheumatoid arthritis, psoriasis, and certain malignancies. Chronic use is associated with hepatotoxicity, specifically the development of hepatic fibrosis and cirrhosis, which necessitates periodic monitoring of liver function tests (LFTs). It is also associated with myelosuppression and pulmonary fibrosis.

Flashcard 2068: The most common side effect of metformin is _____

Answer: GI upset (e.g. nausea, vomiting, anorexia, diarrhea)

Flashcard 2069: Which antacid is associated with hypophosphatemia and osteodystrophy if overused? _____

Answer: Aluminum hydroxide

Flashcard 2070: What drug intoxication presents as emotional lability, slurred speech, ataxia, and blackouts? _____

Answer: Alcohol