Autonomic/CV Drugs — Flashcards

Flashcard 1571: _____-acting benzodiazepines are typically metabolized by the liver into active metabolites.

Answer: Long

Flashcard 1572: Disulfiram is used to discourage _____ consumption

Answer: alcohol

Flashcard 1573: Initially, immune thrombocytopenia (ITP) can be treated with steroids. If it becomes refractory, the patient can be given _____mab. **Bonus:** What drug used in ITP inhibits splenic macrophages?

Answer: Rituximab **Bonus:** IVIG (Intravenous Immunoglobulin)

Extra: Rituximab is a monoclonal antibody against CD20 found on B-cells. IVIG (Intravenous Immunoglobulin) works in ITP by blocking the Fc receptors on splenic macrophages, preventing them from phagocytosing and destroying antibody-coated platelets.

Flashcard 1574: What MSK pathology is associated with heparin use? _____

Answer: Osteoporosis

Flashcard 1575: Valproic acid _____ levels of GABA in the CNS via inhibition of GABA transaminase

Answer: increases

Flashcard 1576: Heparin-induced thrombocytopenia is a disorder that results in platelet _____ secondary to heparin therapy

Answer: activation

Flashcard 1577: Patients with polycythemia vera may take low-dose _____ to decrease risk of thrombosis

Answer: aspirin

Flashcard 1578: Do mineralocorticoid receptor antagonists (e.g. spironolactone, eplerenone) prolong life in heart failure?_____

Answer: Yes

Flashcard 1579: _____ is a PDE-4 inhibitor that is used in severe COPD and may cause abdominal pain, weight loss, and depression.

Answer: Roflumilast

Flashcard 1580: MAO inhibitors are contraindicated in patients taking the anti-tussive _____

Answer: dextromethorphan