_____ is used as an antidote for methanol or ethylene glycol poisoning
_____, a K+ sparing diuretic, may be used to treat symptoms of androgen excess in polycystic ovarian syndrome (PCOS)
Metformin (biguanides) = _____ liver gluconeogenesis (main MOA) and _____ insulin sensitivity
Hint: ↓/↑
Lispro, aspart, glulisine (rapid acting insulin) are useful for controlling the _____ glucose spike
Digitalis can increase heart rate due to _____ of the atria or ventricles
On a dose-response curve: Horizontal shift (EC50) = change in _____ Vertical shift (Emax) = change in _____
Hint: efficacy/potency
What is the mechanism by which β-blockers are able to relieve anginal pain? Decrease _____ → reduces _____
_____ is the most reliable and predictive sign of opioid intoxication
_____ and _____ are two anti-epileptics associated with DRESS (Drug Reaction with Eosinophilia and Systemic Symptoms)
_____ = ↑ risk of rhabdomyolysis
Hint: drug class
Antiarrhythmic classification and mechanisms
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Class I antiarrhythmics (sodium channel blockers)
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Class II antiarrhythmics (beta blockers)
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Class III antiarrhythmics (potassium channel blockers)
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Class IV antiarrhythmics (calcium channel blockers)
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Other antiarrhythmic agents
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Antianginal drugs
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Positive inotropic agents
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Phosphodiesterase inhibitors
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Cardiac glycosides
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Vasopressors and inotropes
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Pulmonary hypertension therapies
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Peripheral vascular disease therapies
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